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Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing—A Translational Example for Intensive Care Units

The prevalence and mortality rates of severe infections are high in intensive care units (ICUs). At the same time, the high pharmacokinetic variability observed in ICU patients increases the risk of inadequate antibiotic drug exposure. Therefore, dosing tailored to specific patient characteristics h...

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Detalles Bibliográficos
Autores principales: Weinelt, Ferdinand Anton, Stegemann, Miriam Songa, Theloe, Anja, Pfäfflin, Frieder, Achterberg, Stephan, Schmitt, Lisa, Huisinga, Wilhelm, Michelet, Robin, Hennig, Stefanie, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708464/
https://www.ncbi.nlm.nih.gov/pubmed/34959409
http://dx.doi.org/10.3390/pharmaceutics13122128