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Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing—A Translational Example for Intensive Care Units
The prevalence and mortality rates of severe infections are high in intensive care units (ICUs). At the same time, the high pharmacokinetic variability observed in ICU patients increases the risk of inadequate antibiotic drug exposure. Therefore, dosing tailored to specific patient characteristics h...
Autores principales: | Weinelt, Ferdinand Anton, Stegemann, Miriam Songa, Theloe, Anja, Pfäfflin, Frieder, Achterberg, Stephan, Schmitt, Lisa, Huisinga, Wilhelm, Michelet, Robin, Hennig, Stefanie, Kloft, Charlotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708464/ https://www.ncbi.nlm.nih.gov/pubmed/34959409 http://dx.doi.org/10.3390/pharmaceutics13122128 |
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