Population Pharmacokinetics and Pharmacodynamic Target Attainment of Isavuconazole against Aspergillus fumigatus and Aspergillus flavus in Adult Patients with Invasive Fungal Diseases: Should Therapeutic Drug Monitoring for Isavuconazole Be Considered as Mandatory as for the Other Mold-Active Azoles?

Isavuconazole is a newer broad-spectrum triazole approved for the treatment of invasive fungal disease. The objective of this study was to conduct a population pharmacokinetic and pharmacodynamic analysis of isavuconazole in a retrospective cohort of hospitalized patients. A nonlinear mixed-effect a...

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Detalles Bibliográficos
Autores principales: Cojutti, Pier Giorgio, Carnelutti, Alessia, Lazzarotto, Davide, Sozio, Emanuela, Candoni, Anna, Fanin, Renato, Tascini, Carlo, Pea, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708495/
https://www.ncbi.nlm.nih.gov/pubmed/34959380
http://dx.doi.org/10.3390/pharmaceutics13122099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708495/
https://www.ncbi.nlm.nih.gov/pubmed/34959380
http://dx.doi.org/10.3390/pharmaceutics13122099

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