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The A179L Gene of African Swine Fever Virus Suppresses Virus-Induced Apoptosis but Enhances Necroptosis

A179L, a non-structural protein of African swine fever virus (ASFV), is capable of suppressing apoptosis by binding the BH3 domain of the pro-apoptotic Bcl-2 family proteins via a conserved ligand binding groove. Our present study aims to determine if A179L affects necroptosis, the second form of pr...

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Detalles Bibliográficos
Autores principales: Shi, Jun, Liu, Wei, Zhang, Miao, Sun, Jing, Xu, Xiulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708531/
https://www.ncbi.nlm.nih.gov/pubmed/34960759
http://dx.doi.org/10.3390/v13122490