Hit Identification of a Novel Quinazoline Sulfonamide as a Promising EphB3 Inhibitor: Design, Virtual Combinatorial Library, Synthesis, Biological Evaluation, and Docking Simulation Studies

EphB3 is a major key player in a variety of cellular activities, including cell migration, proliferation, and apoptosis. However, the exact role of EphB3 in cancer remains ambiguous. Accordingly, new EphB3 inhibitors can increase the understanding of the exact roles of the receptor and may act as pr...

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Detalles Bibliográficos
Autores principales: Lee, Kyeong, Nada, Hossam, Byun, Hyun Jung, Lee, Chang Hoon, Elkamhawy, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708751/
https://www.ncbi.nlm.nih.gov/pubmed/34959648
http://dx.doi.org/10.3390/ph14121247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708751/
https://www.ncbi.nlm.nih.gov/pubmed/34959648
http://dx.doi.org/10.3390/ph14121247

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