Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension

Compound 21 (C21), an AT2 receptor agonist, and Angiotensin 1-7 (Ang 1-7), through Mas receptor, play an important role in the modulation of the protective arm of the renin-angiotensin system. The aim of this study was to investigate in an experimental model of angiotensin II-dependent hypertension...

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Detalles Bibliográficos
Autores principales: Castoldi, Giovanna, Carletti, Raffaella, Ippolito, Silvia, Stella, Andrea, Zerbini, Gianpaolo, Pelucchi, Sara, Zatti, Giovanni, di Gioia, Cira R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708804/
https://www.ncbi.nlm.nih.gov/pubmed/34948475
http://dx.doi.org/10.3390/ijms222413678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708804/
https://www.ncbi.nlm.nih.gov/pubmed/34948475
http://dx.doi.org/10.3390/ijms222413678

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