Mimicking Native Display of CD0873 on Liposomes Augments Its Potency as an Oral Vaccine against Clostridioides difficile

Mucosal vaccination aims to prevent infection mainly by inducing secretory IgA (sIgA) antibody, which neutralises pathogens and enterotoxins by blocking their attachment to epithelial cells. We previously demonstrated that encapsulated protein antigen CD0873 given orally to hamsters induces neutrali...

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Detalles Bibliográficos
Autores principales: Karyal, Cansu, Palazi, Panayiota, Hughes, Jaime, Griffiths, Rhys C., Persaud, Ruby R., Tighe, Patrick J., Mitchell, Nicholas J., Griffin, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708880/
https://www.ncbi.nlm.nih.gov/pubmed/34960199
http://dx.doi.org/10.3390/vaccines9121453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708880/
https://www.ncbi.nlm.nih.gov/pubmed/34960199
http://dx.doi.org/10.3390/vaccines9121453

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