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Formulation of Lipid-Based Tableted Spray-Congealed Microparticles for Sustained Release of Vildagliptin: In Vitro and In Vivo Studies

Spray-congealing (SPC) technology was utilized to prepare lipid-based microparticles (MP) capable of sustaining the release of Vildagliptin (VG) for use as a once-daily treatment for type 2 diabetes mellitus. VG microparticles were prepared using Compritol(®) and Gelucire(®)50/13 as lipid carriers i...

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Detalles Bibliográficos
Autores principales: Al Zahabi, Khaled H., Ben tkhayat, Hind, Abu-Basha, Ehab, Sallam, Al Sayed, Younes, Husam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709051/
https://www.ncbi.nlm.nih.gov/pubmed/34959439
http://dx.doi.org/10.3390/pharmaceutics13122158