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Formulation of Lipid-Based Tableted Spray-Congealed Microparticles for Sustained Release of Vildagliptin: In Vitro and In Vivo Studies
Spray-congealing (SPC) technology was utilized to prepare lipid-based microparticles (MP) capable of sustaining the release of Vildagliptin (VG) for use as a once-daily treatment for type 2 diabetes mellitus. VG microparticles were prepared using Compritol(®) and Gelucire(®)50/13 as lipid carriers i...
Autores principales: | Al Zahabi, Khaled H., Ben tkhayat, Hind, Abu-Basha, Ehab, Sallam, Al Sayed, Younes, Husam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709051/ https://www.ncbi.nlm.nih.gov/pubmed/34959439 http://dx.doi.org/10.3390/pharmaceutics13122158 |
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