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CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet–Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling

Peritonitis and peritonitis-associated sepsis are characterized by an increased formation of platelet–neutrophil complexes (PNCs), which contribute to an excessive migration of polymorphonuclear neutrophils (PMN) into the inflamed tissue. An important neutrophilic mechanism to capture and kill invad...

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Detalles Bibliográficos
Autores principales: Ngamsri, Kristian-Christos, Putri, Rizki A., Jans, Christoph, Schindler, Katharina, Fuhr, Anika, Zhang, Yi, Gamper-Tsigaras, Jutta, Ehnert, Sabrina, Konrad, Franziska M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709064/
https://www.ncbi.nlm.nih.gov/pubmed/34948374
http://dx.doi.org/10.3390/ijms222413576