Intracellularly Released Cholesterol from Polymer-Based Delivery Systems Alters Cellular Responses to Pneumolysin and Promotes Cell Survival

Cholesterol is highly abundant within all human body cells and modulates critical cellular functions related to cellular plasticity, metabolism, and survival. The cholesterol-binding toxin pneumolysin represents an essential virulence factor of Streptococcus pneumoniae in establishing pneumonia and...

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Detalles Bibliográficos
Autores principales: Kammann, Tobias, Hoff, Jessica, Yildirim, Ilknur, Shkodra, Blerina, Müller, Tina, Weber, Christine, Gräler, Markus H., Maus, Ulrich A., Paton, James C., Singer, Mervyn, Traeger, Anja, Schubert, Ulrich S., Bauer, Michael, Press, Adrian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709088/
https://www.ncbi.nlm.nih.gov/pubmed/34940579
http://dx.doi.org/10.3390/metabo11120821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709088/
https://www.ncbi.nlm.nih.gov/pubmed/34940579
http://dx.doi.org/10.3390/metabo11120821

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