Selection of Promising Novel Fragment Sized S. aureus SrtA Noncovalent Inhibitors Based on QSAR and Docking Modeling Studies

Sortase A (SrtA) of Staphylococcus aureus has been identified as a promising target to a new type of antivirulent drugs, and therefore, the design of lead molecules with a low nanomolar range of activity and suitable drug-like properties is important. In this work, we aimed at identifying new fragme...

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Detalles Bibliográficos
Autores principales: Shulga, Dmitry A., Kudryavtsev, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709105/
https://www.ncbi.nlm.nih.gov/pubmed/34946760
http://dx.doi.org/10.3390/molecules26247677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709105/
https://www.ncbi.nlm.nih.gov/pubmed/34946760
http://dx.doi.org/10.3390/molecules26247677

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