Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance

The NAD-dependent deacetylase SIRT1 improves β cell function. Accordingly, nicotinamide mononucleotide (NMN), the product of the rate-limiting step in NAD synthesis, prevents β cell dysfunction and glucose intolerance in mice fed a high-fat diet. The current study was performed to assess the effects...

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Detalles Bibliográficos
Autores principales: Nahle, Ashraf, Joseph, Yemisi Deborah, Pereira, Sandra, Mori, Yusaku, Poon, Frankie, Ghadieh, Hilda E., Ivovic, Aleksandar, Desai, Tejas, Ghanem, Simona S., Asalla, Suman, Muturi, Harrison T., Jentz, Emelien M., Joseph, Jamie W., Najjar, Sonia M., Giacca, Adria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709165/
https://www.ncbi.nlm.nih.gov/pubmed/34948019
http://dx.doi.org/10.3390/ijms222413224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709165/
https://www.ncbi.nlm.nih.gov/pubmed/34948019
http://dx.doi.org/10.3390/ijms222413224

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