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Increased Susceptibility of the CD57(−) NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response

Nowadays, the use of genetically modified NK cells is a promising strategy for cancer immunotherapy. The additional insertion of genes capable of inducing cell suicide allows for the timely elimination of the modified NK cells. Different subsets of the heterogenic NK cell population may differ in pr...

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Detalles Bibliográficos
Autores principales: Palamarchuk, Anastasia I., Alekseeva, Nadezhda A., Streltsova, Maria A., Ustiuzhanina, Maria O., Kobyzeva, Polina A., Kust, Sofya A., Grechikhina, Maria V., Boyko, Anna A., Shustova, Olga A., Sapozhnikov, Alexander M., Kovalenko, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709225/
https://www.ncbi.nlm.nih.gov/pubmed/34948123
http://dx.doi.org/10.3390/ijms222413326