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Hepatitis C Virus Core Protein Down-Regulates Expression of Src-Homology 2 Domain Containing Protein Tyrosine Phosphatase by Modulating Promoter DNA Methylation

Hepatitis C virus (HCV) is the major causative pathogen associated with liver cirrhosis and hepatocellular carcinoma. The main virion component, the core (C) protein, has been implicated in several aspects of HCV pathology including oncogenesis and immune subversion. Here we show that expression of...

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Detalles Bibliográficos
Autores principales: Devi, Priya, Ota, Seisuke, Punga, Tanel, Bergqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709277/
https://www.ncbi.nlm.nih.gov/pubmed/34960785
http://dx.doi.org/10.3390/v13122514