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Inhibition of Viral Membrane Fusion by Peptides and Approaches to Peptide Design

Fusion of lipid-enveloped viruses with the cellular plasma membrane or the endosome membrane is mediated by viral envelope proteins that undergo large conformational changes following binding to receptors. The HIV-1 fusion protein gp41 undergoes a transition into a “six-helix bundle” after binding o...

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Detalles Bibliográficos
Autores principales: Düzgüneş, Nejat, Fernandez-Fuentes, Narcis, Konopka, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709411/
https://www.ncbi.nlm.nih.gov/pubmed/34959554
http://dx.doi.org/10.3390/pathogens10121599