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Inhibition of Viral Membrane Fusion by Peptides and Approaches to Peptide Design
Fusion of lipid-enveloped viruses with the cellular plasma membrane or the endosome membrane is mediated by viral envelope proteins that undergo large conformational changes following binding to receptors. The HIV-1 fusion protein gp41 undergoes a transition into a “six-helix bundle” after binding o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709411/ https://www.ncbi.nlm.nih.gov/pubmed/34959554 http://dx.doi.org/10.3390/pathogens10121599 |