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Metabolic Effects of CCN5/WISP2 Gene Deficiency and Transgenic Overexpression in Mice
CCN5/WISP2 is a matricellular protein, the expression of which is under the regulation of Wnt signaling and IGF-1. Our initial characterization supports the notion that CCN5 might promote the proliferation and survival of pancreatic β-cells and thus improve the metabolic profile of the animals. More...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709456/ https://www.ncbi.nlm.nih.gov/pubmed/34948212 http://dx.doi.org/10.3390/ijms222413418 |