Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells

T cell activation by antigen involves multiple sequential steps, including T cell receptor-microcluster TCR-(MC) formation, immunological synapse formation, and phosphorylation of mediators downstream of the TCR. The adaptor protein, Disc Large Homolog 1 (DLG1), is known to regulate proximal TCR sig...

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Detalles Bibliográficos
Autores principales: Guha, June, Chari, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709471/
https://www.ncbi.nlm.nih.gov/pubmed/34960191
http://dx.doi.org/10.3390/vaccines9121446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709471/
https://www.ncbi.nlm.nih.gov/pubmed/34960191
http://dx.doi.org/10.3390/vaccines9121446

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