Understanding COVID-19 Pathogenesis: A Drug-Repurposing Effort to Disrupt Nsp-1 Binding to Export Machinery Receptor Complex

Non-structural protein 1 (Nsp1) is a virulence factor found in all beta coronaviruses (b-CoVs). Recent studies have shown that Nsp1 of SARS-CoV-2 virus interacts with the nuclear export receptor complex, which includes nuclear RNA export factor 1 (NXF1) and nuclear transport factor 2-like export fac...

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Detalles Bibliográficos
Autores principales: Vasudevan, Sona, Baraniuk, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709492/
https://www.ncbi.nlm.nih.gov/pubmed/34959589
http://dx.doi.org/10.3390/pathogens10121634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709492/
https://www.ncbi.nlm.nih.gov/pubmed/34959589
http://dx.doi.org/10.3390/pathogens10121634

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