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New Approaches to Multi-Parametric HIV-1 Genetics Using Multiple Displacement Amplification: Determining the What, How, and Where of the HIV-1 Reservoir

Development of potential HIV-1 curative interventions requires accurate characterization of the proviral reservoir, defined as host-integrated viral DNA genomes that drive rebound of viremia upon halting ART (antiretroviral therapy). Evaluation of such interventions necessitates methods capable of p...

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Detalles Bibliográficos
Autores principales: Patro, Sean C., Niyongabo, Aurelie, Maldarelli, Frank, Kearney, Mary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709494/
https://www.ncbi.nlm.nih.gov/pubmed/34960744
http://dx.doi.org/10.3390/v13122475