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Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study

BACKGROUND: Lipid metabolism plays an important role in viral infections. We aimed to assess the causal effect of lipid-lowering drugs (HMGCR inhibitiors, PCSK9 inhibitiors, and NPC1L1 inhibitior) on COVID-19 outcomes using two-sample Mendelian randomization (MR) study. METHODS: We used two kinds of...

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Detalles Bibliográficos
Autores principales: Huang, Wuqing, Xiao, Jun, Ji, Jianguang, Chen, Liangwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709572/
https://www.ncbi.nlm.nih.gov/pubmed/34866576
http://dx.doi.org/10.7554/eLife.73873