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Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods

The transcription factor activating protein two gamma (AP2γ) is an important regulator of neurogenesis both during embryonic development as well as in the postnatal brain, but its role for neurophysiology and behavior at distinct postnatal periods is still unclear. In this work, we explored the neur...

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Detalles Bibliográficos
Autores principales: Loureiro-Campos, Eduardo, Mateus-Pinheiro, António, Patrício, Patrícia, Soares-Cunha, Carina, Silva, Joana, Sardinha, Vanessa Morais, Mendes-Pinheiro, Bárbara, Silveira-Rosa, Tiago, Domingues, Ana Verónica, Rodrigues, Ana João, Oliveira, João, Sousa, Nuno, Alves, Nuno Dinis, Pinto, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709574/
https://www.ncbi.nlm.nih.gov/pubmed/34859784
http://dx.doi.org/10.7554/eLife.70685