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SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however, the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here, we investigated direct inflammatory functions of major structural proteins of SARS-CoV-2. We observed that spike (S) protein pot...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709575/ https://www.ncbi.nlm.nih.gov/pubmed/34866574 http://dx.doi.org/10.7554/eLife.68563 |