Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

Heat shock factor 1 (HSF1), a key regulator of transcriptional responses to proteotoxic stress, was linked to estrogen (E2) signaling through estrogen receptor α (ERα). We found that an HSF1 deficiency may decrease ERα level, attenuate the mitogenic action of E2, counteract E2-stimulated cell scatte...

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Detalles Bibliográficos
Autores principales: Vydra, Natalia, Janus, Patryk, Kus, Paweł, Stokowy, Tomasz, Mrowiec, Katarzyna, Toma-Jonik, Agnieszka, Krzywon, Aleksandra, Cortez, Alexander Jorge, Wojtas, Bartosz, Gielniewski, Bartłomiej, Jaksik, Roman, Kimmel, Marek, Widlak, Wieslawa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
https://www.ncbi.nlm.nih.gov/pubmed/34783649
http://dx.doi.org/10.7554/eLife.69843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
https://www.ncbi.nlm.nih.gov/pubmed/34783649
http://dx.doi.org/10.7554/eLife.69843

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