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IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome

Interleukin- (IL-) 38 is an emerging cytokine with multiple functions involved in infection and immunity. However, the potential role of IL-38 in the host immune response during sepsis remains elusive. Herein, we investigated if macrophages in septic mice express IL-38, the molecular mechanisms behi...

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Detalles Bibliográficos
Autores principales: Ge, Yun, Chen, Juan, Hu, Yanting, Chen, Xinyi, Huang, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709774/
https://www.ncbi.nlm.nih.gov/pubmed/34955683
http://dx.doi.org/10.1155/2021/6370911