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Imaging inflammation in atherosclerotic plaques, targeting SST(2) with [(111)In]In-DOTA-JR11

BACKGROUND: Imaging Somatostatin Subtype Receptor 2 (SST(2)) expressing macrophages by [DOTA,Tyr(3)]-octreotate (DOTATATE) has proven successful for plaque detection. DOTA-JR11 is a SST(2) targeting ligand with a five times higher tumor uptake than DOTATATE, and holds promise to improve plaque imagi...

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Detalles Bibliográficos
Autores principales: Meester, Eric J., Krenning, Boudewijn J., de Blois, Erik, de Jong, Marion, van der Steen, Antonius F. W., Bernsen, Monique R., van der Heiden, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709817/
https://www.ncbi.nlm.nih.gov/pubmed/32026330
http://dx.doi.org/10.1007/s12350-020-02046-y