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Imaging inflammation in atherosclerotic plaques, targeting SST(2) with [(111)In]In-DOTA-JR11
BACKGROUND: Imaging Somatostatin Subtype Receptor 2 (SST(2)) expressing macrophages by [DOTA,Tyr(3)]-octreotate (DOTATATE) has proven successful for plaque detection. DOTA-JR11 is a SST(2) targeting ligand with a five times higher tumor uptake than DOTATATE, and holds promise to improve plaque imagi...
Autores principales: | Meester, Eric J., Krenning, Boudewijn J., de Blois, Erik, de Jong, Marion, van der Steen, Antonius F. W., Bernsen, Monique R., van der Heiden, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709817/ https://www.ncbi.nlm.nih.gov/pubmed/32026330 http://dx.doi.org/10.1007/s12350-020-02046-y |
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