Cargando…

Elimination of negative feedback in TLR signalling allows rapid and hypersensitive detection of microbial contaminants

The exquisite specificity of Toll-like receptors (TLRs) to sense microbial molecular signatures is used as a powerful tool to pinpoint microbial contaminants. Various cellular systems, from native human blood cells to transfected cell lines exploit TLRs as pyrogen detectors in biological preparation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seumen, Clovis H. T., Tomasiunaite, Urte, Legler, Daniel F., Hauck, Christof R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709846/ https://www.ncbi.nlm.nih.gov/pubmed/34952917 http://dx.doi.org/10.1038/s41598-021-03618-9

Ejemplares similares

Protein phosphatases in TLR signaling
por: Seumen, Clovis H. T., et al.
Publicado: (2021)

Maggot Instructor: Semi-Automated Analysis of Learning and Memory in Drosophila Larvae
por: Tomasiunaite, Urte, et al.
Publicado: (2018)

Emerging Technologies for Aerial Decontamination of Food Storage Environments to Eliminate Microbial Cross-Contamination
por: Oliveira, Márcia, et al.
Publicado: (2020)

Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination
por: Choteau, Laura, et al.
Publicado: (2017)

Rapid regrowth and detection of microbial contaminants in equine fecal microbiome samples
por: Beckers, Kalie F., et al.
Publicado: (2017)

Approaches for the Elimination of Microbial Contaminants from Lippia multiflora Mold. Leaves Intended for Tea Bagging and Evaluation of Formulation
por: Kumadoh, Doris, et al.
Publicado: (2022)

Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation
por: Li, Yingju, et al.
Publicado: (2015)

Contaminants in the cow's milk we consume? Pasteurization and other technologies in the elimination of contaminants
por: Calahorrano-Moreno, Micaela Belen, et al.
Publicado: (2022)

TLR2 Regulates Neutrophil Recruitment and Cytokine Production with Minor Contributions from TLR9 during Hypersensitivity Pneumonitis
por: Andrews, Kelly, et al.
Publicado: (2013)

Downregulation of TLR4 by miR-181a Provides Negative Feedback Regulation to Lipopolysaccharide-Induced Inflammation
por: Jiang, Kangfeng, et al.
Publicado: (2018)

MicroRNA-106a Provides Negative Feedback Regulation in Lipopolysaccharide-Induced Inflammation by targeting TLR4
por: Yang, Jing, et al.
Publicado: (2019)

Alternative Polyadenylation Allows Differential Negative Feedback of Human miRNA miR-579 on Its Host Gene ZFR
por: Hinske, Ludwig Christian, et al.
Publicado: (2015)

Aseptic Barriers Allow a Clean Contact for Contaminated Stethoscope Diaphragms
por: Vasudevan, Rajiv, et al.
Publicado: (2020)

Granulocyte CEACAM3 Is a Phagocytic Receptor of the Innate Immune System that Mediates Recognition and Elimination of Human-specific Pathogens
por: Schmitter, Tim, et al.
Publicado: (2004)

Feedback system for elimination of the transverse mode coupling instability
por: Danilov, V V, et al.
Publicado: (1993)

Chitin amendments eliminate the negative impacts of continuous cropping obstacles on soil properties and microbial assemblage
por: Fan, Yanli, et al.
Publicado: (2022)

Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Improves β-Cell Function Under Stress
por: Gurevitch, Diana, et al.
Publicado: (2010)

Do open garbage dumps play a role in canine rabies transmission in Biyem-Assi health district in Cameroon?
por: Raymond, Tabue N., et al.
Publicado: (2015)

Flexible Switching of Feedback Control Mechanisms Allows for Learning of Different Task Dynamics
por: White, Olivier, et al.
Publicado: (2013)

Hypersensitivity Pneumonitis Caused by a Home Ultrasonic Humidifier Contaminated with Candida guilliermondii
por: Ando, Akemi, et al.
Publicado: (2017)

Cyclophosphamide eliminates suppressor T cells in age-associated central regulation of delayed hypersensitivity in mice
Publicado: (1979)

Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors
por: Fernández-Arjona, María del Mar, et al.
Publicado: (2019)

Microbial contamination in water-based metalworking fluid as trigger for occupational hypersensitivity pneumonitis – development of specific IgG tools for a suspected clinical case
por: Kespohl, Sabine, et al.
Publicado: (2020)

Plant‐driven changes in soil microbial communities influence seed germination through negative feedbacks
por: Miller, Elizabeth C., et al.
Publicado: (2019)

Elimination of the Femoral Neck in Measuring Femoral Version Allows for Less Variance in Interobserver Reliability
por: Dimovski, Radomir, et al.
Publicado: (2021)

Rapid and reagentless detection of microbial contamination within meat utilizing a smartphone-based biosensor
por: Liang, Pei-Shih, et al.
Publicado: (2014)

Colitis-Induced Microbial Perturbation Promotes Postinflammatory Visceral Hypersensitivity
por: Esquerre, Nicolas, et al.
Publicado: (2020)

Self-Collected Gargle Lavage Allows Reliable Detection of SARS-CoV-2 in an Outpatient Setting
por: Zander, Johannes, et al.
Publicado: (2021)

Positive Feedback Promotes Oscillations in Negative Feedback Loops
por: Ananthasubramaniam, Bharath, et al.
Publicado: (2014)

Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors
por: Jurga, Agnieszka M., et al.
Publicado: (2018)

Binding of Gamma-Glutamyl Transferase to TLR4 Signalling Allows Tissue Factor Activation in Monocytes
por: Sanguinetti, Chiara, et al.
Publicado: (2022)

Bronchoalveolar lavage lymphocytosis in hypersensitivity pneumonitis: a retrospective cohort analysis with elimination of incorporation bias
por: Hill, Meghan, et al.
Publicado: (2022)

Myeloid cells protect corneal nerves against sterile injury through negative-feedback regulation of TLR2–IL-6 axis
por: Lee, Hyun Ju, et al.
Publicado: (2023)

Dual-Antigen System Allows Elimination of False Positive Results in COVID-19 Serological Testing
por: Komarov, Andrei, et al.
Publicado: (2021)

Relationship between malaria, anaemia, nutritional and socio-economic status amongst under-ten children, in the North Region of Cameroon: A cross-sectional assessment
por: Sakwe, Nobelle, et al.
Publicado: (2019)

Microbial contamination and disinfection methods of pacifiers
por: NELSON, Paulo, et al.
Publicado: (2015)

Prevalence of microbial contamination in donor corneas
por: Chen, Nan-Ni, et al.
Publicado: (2019)

Microbial Cleaning for Removal of Surface Contamination
por: Kohli, Rajiv
Publicado: (2013)

Microbial Contamination and Public Health: An Overview
por: Tropea, Alessia
Publicado: (2022)

The Sunny Side of Negative Feedback: Negative Feedback Enhances One’s Motivation to Win in Another Activity
por: Fang, Hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_erat9vc8prapt6k97e956dirsh