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Impact of limb amputation and cisplatin chemotherapy on metastatic progression in mouse models of osteosarcoma

Development of animal models that accurately recapitulate human cancer is an ongoing challenge. This is particularly relevant in the study of osteosarcoma (OS), a highly malignant bone tumor diagnosed in approximately 1000 pediatric/adolescent patients each year. Metastasis is the leading cause of p...

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Detalles Bibliográficos
Autores principales: Ren, L., Huang, S., Beck, J., LeBlanc, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709858/
https://www.ncbi.nlm.nih.gov/pubmed/34952927
http://dx.doi.org/10.1038/s41598-021-04018-9