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PINK1 signalling in neurodegenerative disease

PTEN-induced kinase 1 (PINK1) impacts cell health and human pathology through diverse pathways. The strict processing of full-length PINK1 on the outer mitochondrial membrane populates a cytoplasmic pool of cleaved PINK1 (cPINK1) that is constitutively degraded. However, despite rapid proteasomal cl...

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Detalles Bibliográficos
Autores principales: Whiten, Daniel R., Cox, Dezerae, Sue, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709887/
https://www.ncbi.nlm.nih.gov/pubmed/34897410
http://dx.doi.org/10.1042/EBC20210036