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Cryo-EM structures of τ filaments from human brain
Electron cryo-microscopy (cryo-EM) has made it possible to determine near-atomic structures of τ filaments from human brain. Previous work had shown that the cores of paired helical and straight filaments of Alzheimer's disease are made of two identical, but differently arranged C-shaped protof...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Portland Press Ltd.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709893/ https://www.ncbi.nlm.nih.gov/pubmed/34846514 http://dx.doi.org/10.1042/EBC20210025 |