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Cryo-EM structures of τ filaments from human brain

Electron cryo-microscopy (cryo-EM) has made it possible to determine near-atomic structures of τ filaments from human brain. Previous work had shown that the cores of paired helical and straight filaments of Alzheimer's disease are made of two identical, but differently arranged C-shaped protof...

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Detalles Bibliográficos
Autor principal:	Goedert, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Molecular Bases of Health & Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709893/ https://www.ncbi.nlm.nih.gov/pubmed/34846514 http://dx.doi.org/10.1042/EBC20210025

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