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DC-SIGN targets amphotericin B-loaded liposomes to diverse pathogenic fungi

BACKGROUND: Life-threatening invasive fungal infections are treated with antifungal drugs such as Amphotericin B (AmB) loaded liposomes. Our goal herein was to show that targeting liposomal AmB to fungal cells with the C-type lectin pathogen recognition receptor DC-SIGN improves antifungal activity....

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Detalles Bibliográficos
Autores principales: Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A., Lin, Xiaorong, Meagher, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709943/
https://www.ncbi.nlm.nih.gov/pubmed/34952645
http://dx.doi.org/10.1186/s40694-021-00126-3