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DC-SIGN targets amphotericin B-loaded liposomes to diverse pathogenic fungi
BACKGROUND: Life-threatening invasive fungal infections are treated with antifungal drugs such as Amphotericin B (AmB) loaded liposomes. Our goal herein was to show that targeting liposomal AmB to fungal cells with the C-type lectin pathogen recognition receptor DC-SIGN improves antifungal activity....
Autores principales: | Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A., Lin, Xiaorong, Meagher, Richard B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709943/ https://www.ncbi.nlm.nih.gov/pubmed/34952645 http://dx.doi.org/10.1186/s40694-021-00126-3 |
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