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Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression

BACKGROUND: N6-methyladenosine (m6A), the most abundant and reversible modification of mRNAs in eukaryotes, plays pivotal role in breast cancer (BC) tumorigenesis and progression. Circular RNAs (circRNAs) can act as tumor promoters or suppressors by microRNA (miRNA) sponges in BC. However, the under...

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Detalles Bibliográficos
Autores principales: Lv, Wenchang, Tan, Yufang, Xiong, Mingchen, Zhao, Chongru, Wang, Yichen, Wu, Min, Wu, Yiping, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709995/
https://www.ncbi.nlm.nih.gov/pubmed/34952600
http://dx.doi.org/10.1186/s12967-021-03196-4