cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries

BACKGROUND: Exogenous cDNA introduced into an experimental system, either intentionally or accidentally, can appear as added read coverage over that gene in next-generation sequencing libraries derived from this system. If not properly recognized and managed, this cross-contamination with exogenous...

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Detalles Bibliográficos
Autores principales: Qi, Meifang, Nayar, Utthara, Ludwig, Leif S., Wagle, Nikhil, Rheinbay, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709999/
https://www.ncbi.nlm.nih.gov/pubmed/34952565
http://dx.doi.org/10.1186/s12859-021-04529-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709999/
https://www.ncbi.nlm.nih.gov/pubmed/34952565
http://dx.doi.org/10.1186/s12859-021-04529-2

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