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Transcriptional Interactomic Inhibition of RORα Suppresses Th17-Related Inflammation

PURPOSE: Th17 cells and their cytokines are implicated in the pathogenesis of various autoimmune diseases. Retinoic acid-related orphan receptor alpha (RORα) is a transcription factor for the differentiation and the inflammatory functions of Th17 cells. In this study, we generated the nucleus-transd...

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Detalles Bibliográficos
Autores principales: Ho, Chun-Chang, Kim, Giha, Mun, Chin Hee, Kim, Ju-Won, Han, Jieun, Park, Ji Yoon, Park, Yong-Beom, Lee, Sang-Kyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710077/
https://www.ncbi.nlm.nih.gov/pubmed/34992408
http://dx.doi.org/10.2147/JIR.S344031