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Transcriptional Interactomic Inhibition of RORα Suppresses Th17-Related Inflammation
PURPOSE: Th17 cells and their cytokines are implicated in the pathogenesis of various autoimmune diseases. Retinoic acid-related orphan receptor alpha (RORα) is a transcription factor for the differentiation and the inflammatory functions of Th17 cells. In this study, we generated the nucleus-transd...
Autores principales: | Ho, Chun-Chang, Kim, Giha, Mun, Chin Hee, Kim, Ju-Won, Han, Jieun, Park, Ji Yoon, Park, Yong-Beom, Lee, Sang-Kyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710077/ https://www.ncbi.nlm.nih.gov/pubmed/34992408 http://dx.doi.org/10.2147/JIR.S344031 |
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