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Efficacy of Immune Checkpoint Inhibitors in Patients with Mismatch Repair-Deficient or Microsatellite Instability-High Metastatic Colorectal Cancer: Analysis of Three Phase-II Trials

Programmed cell death ligand 1 (PD-L1) and programmed cell death protein 1 (PD-1) inhibitors are increasingly used in a variety of solid tumors. In patients with DNA mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) metastatic colorectal cancer, their efficacy has been demonst...

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Detalles Bibliográficos
Autores principales: Cancanelli, Luca, Rivano, Melania, Di Spazio, Lorenzo, Chiumente, Marco, Mengato, Daniele, Messori, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710086/
https://www.ncbi.nlm.nih.gov/pubmed/34966607
http://dx.doi.org/10.7759/cureus.19893