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Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro

The well‐established 3D organoid culture method enabled efficient expansion of cholangiocyte‐like cells from intrahepatic (IHBD) and extrahepatic bile duct (EHBD) tissue biopsies. The extensive expansion capacity of these organoids enables various applications, from cholangiocyte disease modelling t...

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Detalles Bibliográficos
Autores principales: Roos, Floris J. M., Wu, Haoyu, Willemse, Jorke, Lieshout, Ruby, Albarinos, Laura A. Muñoz, Kan, Yik‐Yang, Poley, Jan‐Werner, Bruno, Marco J., de Jonge, Jeroen, Bártfai, Richard, Marks, Hendrik, IJzermans, Jan N. M., Verstegen, Monique M. A., van der Laan, Luc J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710298/
https://www.ncbi.nlm.nih.gov/pubmed/34954911
http://dx.doi.org/10.1002/ctm2.566