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Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro
The well‐established 3D organoid culture method enabled efficient expansion of cholangiocyte‐like cells from intrahepatic (IHBD) and extrahepatic bile duct (EHBD) tissue biopsies. The extensive expansion capacity of these organoids enables various applications, from cholangiocyte disease modelling t...
Autores principales: | Roos, Floris J. M., Wu, Haoyu, Willemse, Jorke, Lieshout, Ruby, Albarinos, Laura A. Muñoz, Kan, Yik‐Yang, Poley, Jan‐Werner, Bruno, Marco J., de Jonge, Jeroen, Bártfai, Richard, Marks, Hendrik, IJzermans, Jan N. M., Verstegen, Monique M. A., van der Laan, Luc J. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710298/ https://www.ncbi.nlm.nih.gov/pubmed/34954911 http://dx.doi.org/10.1002/ctm2.566 |
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