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Endocytosis mediated by an atypical CUBAM complex modulates slit diaphragm dynamics in nephrocytes

The vertebrate endocytic receptor CUBAM, consisting of three cubilin monomers complexed with a single amnionless molecule, plays a major role in protein reabsorption in the renal proximal tubule. Here, we show that Drosophila CUBAM is a tripartite complex composed of Amnionless and two cubilin paral...

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Detalles Bibliográficos
Autores principales: Atienza-Manuel, Alexandra, Castillo-Mancho, Vicente, De Renzis, Stefano, Culi, Joaquim, Ruiz-Gómez, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710305/
https://www.ncbi.nlm.nih.gov/pubmed/34738617
http://dx.doi.org/10.1242/dev.199894