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Phosphoproteomic Analysis Reveals Downstream PKA Effectors of AKAP Cypher/ZASP in the Pathogenesis of Dilated Cardiomyopathy

Background: Dilated cardiomyopathy (DCM) is a major cause of heart failure worldwide. The Z-line protein Cypher/Z-band alternatively spliced PDZ-motif protein (ZASP) is closely associated with DCM, both clinically and in animal models. Our earlier work revealed Cypher/ZASP as a PKA-anchoring protein...

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Detalles Bibliográficos
Autores principales: Lv, Jialan, Pan, Zhicheng, Chen, Jian, Xu, Rui, Wang, Dongfei, Huang, Jiaqi, Dong, Yang, Jiang, Jing, Yin, Xiang, Cheng, Hongqiang, Guo, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710605/
https://www.ncbi.nlm.nih.gov/pubmed/34966794
http://dx.doi.org/10.3389/fcvm.2021.753072