Cargando…
Phosphoproteomic Analysis Reveals Downstream PKA Effectors of AKAP Cypher/ZASP in the Pathogenesis of Dilated Cardiomyopathy
Background: Dilated cardiomyopathy (DCM) is a major cause of heart failure worldwide. The Z-line protein Cypher/Z-band alternatively spliced PDZ-motif protein (ZASP) is closely associated with DCM, both clinically and in animal models. Our earlier work revealed Cypher/ZASP as a PKA-anchoring protein...
Autores principales: | Lv, Jialan, Pan, Zhicheng, Chen, Jian, Xu, Rui, Wang, Dongfei, Huang, Jiaqi, Dong, Yang, Jiang, Jing, Yin, Xiang, Cheng, Hongqiang, Guo, Xiaogang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710605/ https://www.ncbi.nlm.nih.gov/pubmed/34966794 http://dx.doi.org/10.3389/fcvm.2021.753072 |
Ejemplares similares
-
The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac Ca(V)1.2 calcium channels
por: Yu, Haijie, et al.
Publicado: (2018) -
Downregulation of Cypher induces apoptosis in cardiomyocytes via Akt/p38 MAPK signaling pathway
por: Xuan, Tianming, et al.
Publicado: (2020) -
Novel polymorphisms in PDLIM3 and PDLIM5 gene encoding Z‐line proteins increase risk of idiopathic dilated cardiomyopathy
por: Wang, Dongfei, et al.
Publicado: (2019) -
MAGGIC Risk Model Predicts Adverse Events and Left Ventricular Remodeling in Non-Ischemic Dilated Cardiomyopathy
por: Dong, Yang, et al.
Publicado: (2020) -
Learning Cypher
por: Panzarino, Onofrio
Publicado: (2014)