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Nicotine Oral Administration Attenuates DSS-Induced Colitis Through Upregulation of Indole in the Distal Colon and Rectum in Mice

Nicotine affects the gastrointestinal environment and modulates ulcerative colitis (UC). However, the associations among nicotine, gut metabolites, and UC are still largely unknown. We investigated whether orally administered nicotine affected gut metabolites and dextran sodium sulfate (DSS)-induced...

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Detalles Bibliográficos
Autores principales: Nakajima, Akihito, Shibuya, Tomoyoshi, Sasaki, Takashi, Lu, Yu Jie, Ishikawa, Dai, Haga, Keiichi, Takahashi, Masahito, Kaga, Naoko, Osada, Taro, Sato, Nobuhiro, Nagahara, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710606/
https://www.ncbi.nlm.nih.gov/pubmed/34966763
http://dx.doi.org/10.3389/fmed.2021.789037