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Case Report: Early Association of Vemurafenib to Standard Chemotherapy in Multisystem Langerhans Cell Histiocytosis in a Newborn: Taking a Chance for a Better Outcome?

Langerhans cell histiocytosis (LCH) is due to aberrant monoclonal proliferation and accumulation of dendritic cells, ranging from a self-limiting local condition to a rapidly progressive multisystem disease with poor prognosis. Pathogenic cells originate from a myeloid-derived precursor characterize...

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Detalles Bibliográficos
Autores principales: Gaspari, Stefania, Di Ruscio, Valentina, Stocchi, Francesca, Carta, Roberto, Becilli, Marco, De Ioris, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710608/
https://www.ncbi.nlm.nih.gov/pubmed/34966688
http://dx.doi.org/10.3389/fonc.2021.794498