Cardioprotective effects of dantrolene in doxorubicin-induced cardiomyopathy in mice

BACKGROUND: Doxorubicin (Dox) is a potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. Intracellular calcium dysregulation has been reported to be involved in doxorubicin-induced cardiomyopathy (DICM). The cardioprotective role of RyR stabilizer dantrolene (Dan)...

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Detalles Bibliográficos
Autores principales: Azam, Mohammed Ali, Chakraborty, Praloy, Bokhari, Mahmoud M., Dadson, Keith, Du, Beibei, Massé, Stéphane, Si, Daoyuan, Niri, Ahmed, Aggarwal, Arjun K., Lai, Patrick F.H., Riazi, Sheila, Billia, Filio, Nanthakumar, Kumaraswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Arrhythmic Risk in Cardiomyopathy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710625/
https://www.ncbi.nlm.nih.gov/pubmed/34988524
http://dx.doi.org/10.1016/j.hroo.2021.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710625/
https://www.ncbi.nlm.nih.gov/pubmed/34988524
http://dx.doi.org/10.1016/j.hroo.2021.08.008

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