Cargando…

Cardioprotective effects of dantrolene in doxorubicin-induced cardiomyopathy in mice

BACKGROUND: Doxorubicin (Dox) is a potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. Intracellular calcium dysregulation has been reported to be involved in doxorubicin-induced cardiomyopathy (DICM). The cardioprotective role of RyR stabilizer dantrolene (Dan)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Azam, Mohammed Ali, Chakraborty, Praloy, Bokhari, Mahmoud M., Dadson, Keith, Du, Beibei, Massé, Stéphane, Si, Daoyuan, Niri, Ahmed, Aggarwal, Arjun K., Lai, Patrick F.H., Riazi, Sheila, Billia, Filio, Nanthakumar, Kumaraswamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Arrhythmic Risk in Cardiomyopathy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710625/ https://www.ncbi.nlm.nih.gov/pubmed/34988524 http://dx.doi.org/10.1016/j.hroo.2021.08.008

Ejemplares similares

Sacubitril/valsartan versus angiotensin inhibitors and arrhythmia endpoints in heart failure with reduced ejection fraction
por: Fernandes, Amanda D.F., et al.
Publicado: (2021)

Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats
por: Du, Beibei, et al.
Publicado: (2020)

Statins Protect Against Early Stages of Doxorubicin-induced Cardiotoxicity Through the Regulation of Akt Signaling and SERCA2
por: Dadson, Keith, et al.
Publicado: (2022)

Synchronizing systolic calcium release with azumolene in an experimental model
por: Si, Daoyuan, et al.
Publicado: (2022)

Uncoupling cytosolic calcium from membrane voltage by transient receptor potential melastatin 4 channel (TRPM4) modulation: A novel strategy to treat ventricular arrhythmias
por: Chakraborty, Praloy, et al.
Publicado: (2023)

Left Ventricular Assist Device With a Left Atrial Inflow Cannula for Hypertrophic Cardiomyopathy
por: Kiamanesh, Omid, et al.
Publicado: (2020)

Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation
por: Van, Serena, et al.
Publicado: (2021)

Desmin Mutations and Arrhythmogenic Right Ventricular Cardiomyopathy
por: Lorenzon, Alessandra, et al.
Publicado: (2013)

Heart Rate Recovery in Patients With Hypertrophic Cardiomyopathy
por: Patel, Vimal, et al.
Publicado: (2014)

Myofibrillar Cardiomyopathy due to a Novel Desmin Gene Mutation: Complementary Role of Echocardiography, Cardiac Magnetic Resonance, and Genetic Testing in Delineating Diagnosis
por: Koitka, Karen, et al.
Publicado: (2017)

Cough-Induced Takotsubo (Stress) Cardiomyopathy
por: Lal, Sudish, et al.
Publicado: (2018)

The left atrium in cardiac amyloidosis: a valuable but still underused observation window on the overall disease process
por: Rapezzi, Claudio, et al.
Publicado: (2021)

Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma
por: Narayan, Hari K, et al.
Publicado: (2019)

Maximizing detection and optimal characterization of local abnormal ventricular activity in nonischemic cardiomyopathy: LAVA(MAX) & LAVA(FLOW)
por: Magtibay, Karl, et al.
Publicado: (2021)

Orthogonal bipolar approach to detect cardiac repolarization changes related to activation direction
por: Masse, S, et al.
Publicado: (2023)

The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1
por: Dadson, Keith, et al.
Publicado: (2017)

Orientation of conduction velocity vectors on cardiac mapping surfaces
por: Padilla, Jairo Rodriguez, et al.
Publicado: (2023)

Pro-arrhythmic role of adrenergic spatial densities in the human atria: An in-silico study
por: Magtibay, Karl, et al.
Publicado: (2023)

Malignant hyperthermia and dantrolene sodium
por: Kim, Ha Jung, et al.
Publicado: (2019)

Dantrolene Attenuates Cardiotoxicity of Doxorubicin Without Reducing its Antitumor Efficacy in a Breast Cancer Model
por: Todorova, Valentina K., et al.
Publicado: (2020)

Intravenous dantrolene in hypermetabolic syndromes: a survey of the U.S. Veterans Health Administration database
por: Caroff, Stanley N., et al.
Publicado: (2022)

HYBRID MANAGEMENT OF HEART FAILURE DURING THE COVID-19 PANDEMIC AFTER ADOPTION OF A TELEHEALTH MODEL
por: Hadi, M. Azam, et al.
Publicado: (2022)

Current clinical application of dantrolene sodium
por: Yang, Hong Seuk, et al.
Publicado: (2023)

Myocardial recovery following durable left ventricular assist device support
por: Rao, Vivek, et al.
Publicado: (2021)

Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy
por: Kuusisto, Johanna, et al.
Publicado: (2012)

Multimodality Imaging in Hypereosinophilic Syndrome With Cardiac Involvement
por: Arunachalam, Karuppiah, et al.
Publicado: (2019)

Takotsubo-Like Cardiomyopathy in Pheochromocytoma
por: Su, Zhongzhou, et al.
Publicado: (2019)

Sex‐ and age‐based differences in the natural history and outcome of dilated cardiomyopathy
por: Halliday, Brian P., et al.
Publicado: (2018)

The systolic paradox in hypertrophic cardiomyopathy
por: Haland, Trine F, et al.
Publicado: (2017)

Biventricular pacemaker therapy improves exercise capacity in patients with non‐obstructive hypertrophic cardiomyopathy via augmented diastolic filling on exercise
por: Ahmed, Ibrar, et al.
Publicado: (2020)

One Patient, Three Variants, Four Episodes of Takotsubo Cardiomyopathy
por: Frankel, Eitan, et al.
Publicado: (2020)

Acute Myeloid Leukemia Presenting as Effusive Constrictive Pericarditis
por: Lutz, Andrew, et al.
Publicado: (2019)

Hypertensive disorders in women with peripartum cardiomyopathy: insights from the ESC EORP PPCM Registry
por: Jackson, Alice M., et al.
Publicado: (2021)

When to start paediatric testing of the adult HIV cure research agenda?
por: Shah, Seema K
Publicado: (2017)

Risk and radical uncertainty in HIV research
por: Hare, Caspar
Publicado: (2017)

Malignant hyperthermia when dantrolene is not readily available
por: Gong, Xiaodan
Publicado: (2021)

Quercetin-induced cardioprotection against doxorubicin cytotoxicity
por: Chen, Jing-Yi, et al.
Publicado: (2013)

Clinical significance of conduction velocity orientation vectors on cardiac mapping surfaces
por: Rodriguez Padilla, J, et al.
Publicado: (2023)

Malignant hyperthermia: Dantrolene sodium - A must have
por: Sharma, Alok, et al.
Publicado: (2012)

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model
por: Chen, Xi, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_i4lecb4fjvtk707dh1rcev5ec6