Downregulation of IRF2 Alleviates Sepsis-Related Acute Kidney Injury in vitro and in vivo

OBJECTIVE: We investigated the roles and mechanisms of IRF2 in sepsis-related acute kidney injury (S-AKI) in a lipopolysaccharide (LPS)-induced HK-2 cell line and caecal ligation and puncture (CLP)-induced IRF2(−/−) mouse model. METHODS: Quantitative real-time polymerase chain reaction assay was use...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, Zhang, Yun, Yang, Aixiang, Xia, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710674/
https://www.ncbi.nlm.nih.gov/pubmed/34992348
http://dx.doi.org/10.2147/DDDT.S334518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710674/
https://www.ncbi.nlm.nih.gov/pubmed/34992348
http://dx.doi.org/10.2147/DDDT.S334518

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